How Does Glyphosate Work – Science Study

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How Does Glyphosate Work?


How Does Glyphosate Work – Do You Right

The process in which glyphosate works to kill plants is through a combination of biological processes. I remember learning about this at TruGreen Chemlawn and Lawn Doctor when I used to apply these chemicals…

How Does Glyphosate Work – Agricultural Magnetism

Glyphosate is a Systemic Herbicide

Systemic herbicidesare added to water to create a solution that is then sprayed on a live plant. The chemicals present in the aqueous mixture is then applied to the plants. Then, the chemical is absorbed through the plant’s tissue.


This is possible because the outside of the cells of the plant are made of a semipermeable membrane. This allows particles of a certain size or weight to pass through.

 Rate of Passage

The rate of passage depends on many factors as well. Concentration, pressure, temperature, and eventually sought solubility, chemistry, or even the properties of a chemical, can have something to do with the rate of passage. It gets way more technical than that, but it basically the process called facilitated diffusion.

To change the topic some, before we get into a whole biology lesson here… You asked how does glyphosate work?

How Does GLyphosate Work?
How Does GLyphosate Work?

Phloem Loading

Once the glyphosate is allowed to pass through the cell walls of the plant, they are present in the plant’s phloem. Once in the plants’ phloem, the glyphosate is translocated through the plants’ phloem via the plants’ cytoplasm by way of symplastic flow. (symplastically) . This is the same process that is used by the plant to bring nutrients from the roots to the tissues.

Once in motion, the chemicals follow the source-sink photosynthate movement pattern in the plant. In other words, they go to the places in the plant where all the nutrients normally go. Moreover, they go to the parts of the plant used for growth and photosynthesis. (Where the plant needs its nutrients the most. These points or “sinks” are also known as meristems.(areas of active growth in the plant)

The chemicals accumulate in these areas and kill the root very quickly because they trick the plant into not growing. In other words, they blind and paralyze the plant. The plant will not grow, photosynthesis will stop, and it will not take in water, or even interpret sunlight. Glyphosate has a special route that it uses to work on the plants.

How Does Glyphosate Work
How Does Glyphosate Work

Glyphosate kills plants on a molecular level by entering and interfering with the synthesis of aromatic amino acids. It manipulates the shikimate pathway and prevents the production of tyrosine, tryptophan, and phenylalanine.

By Tyrosine_biosynthesis.png: Physchim62derivative work: Shakiestone - This file was derived from  Tyrosine biosynthesis.png:, CC BY-SA 3.0,
By Tyrosine_biosynthesis.png: Physchim62derivative work: Shakiestone – This file was derived from  Tyrosine biosynthesis.png:, CC BY-SA 3.0,

Once glyphosate is in the shikimate pathway, it works by inhibiting the production of the enzyme 5-enolpyruvylshikimate-3-phosphate synthase, better known as EPSPS. (Thank goodness LOL) .

This manipulates the biological processes and chemical reactions within the shikimate pathway and causes shikimate to accumulate in the plants’ tissues, therefore, inhibiting the production of certain compounds much needed by the plant.  By diverting the energy and resources away from the plants’ other processes, the plant growth stops within a couple of hours.

Here is Wikipedias version: “glyphosate functions by occupying the binding site of the phosphoenolpyruvate, mimicking an intermediate state of the ternary enzyme-substrate complex.” -Wikipedia contributors, 7 December 2017 15:54 UTC.


How Soon Do the Plants Die?

I didn’t want to confuse you here. On the inside, the plant stops growth within a couple of hours. On the outside, it takes anywhere from a day to several days for the leaves to start turning yellow. So, in short, once glyphosate gets into a plant, it’s over.

Tolerance to Glyphosate

Certain broadleaf weeds have been developing building up tolerances or becoming immune to glyphosate. One doctor, this done a ton of research on this topic, is Stephen C Wellerfrom Purdue College of Agriculture.

Dr. Stephen C. Weller is a weed doctor. He has a Ph.D. and other degrees relative to agriculture. Dr. Weller’s curriculum vitae is hereif you are curious. has done numerous studies on the effects of glyphosate on plants as well as the tolerance that the plants develop to glyphosate.

More importantly, Dr. Weller wrote information on how to manage the crops, in order to combat the immunity affecting crops. You can find much more information about this topic on the following three sources:

Stephen C Weller Ph.D.

Known for his work in agriculture, his vast education in his chosen related fields of study, and his numerous research papers available here.

Research Topics:

  • Glyphosate-Resistant Crops
  • How to Combat Glyphosate-Resistant Crops
  • Various Other Crop Related Articles to Help Farmers.

 Dr. Stephanie Seneff Ph.D

Dr. Stephanie Seneff Ph.D. is MIT’s Senior Research Scientistfor the Computer Science and Artificial Intelligence Laboratory.  Dr. Seneff is a highly respected doctor, student, researcher, and friend to many.

Dr. Seneff has done extensive research on the effects of glyphosate on our health. Dr. Seneff has uncovered some truly gruesome truths behind why our health issues have been on the rise, and could even lead to epidemic proportions soon.

Research Topics:

Glyphosate and Autism

Is Glyphosate the “Safe” Herbicide that’s Making Us All Sick

Death as a Drug Side Effect in FAERS: Is Glyphosate Contamination a Factor?

And Much, Much More!

Young corn field landscape

More Research on Glyphosate!


Glyphosate by

Introduction to Weeds and Herbicides

Do You Right Pro

Social Responsibility Blog

 Please Check Out My Other Blogs on Glyphosate~ !  and my blog on the connection between glyphosate and autism. Dr. Stephanie Seneff is among one of the smartest and sweetest people I have ever met, and she is letting me work with her personally on this topic to get something done about it! 


Wikipedia contributors. “Semipermeable membrane.” Wikipedia, The Free Encyclopedia. Wikipedia, The Free Encyclopedia, 21 Nov. 2017. Web. 8 Dec. 2017. retrieved from

Herbicide. (2017, December 6). In Wikipedia, The Free Encyclopedia. Retrieved 18:57, December 8, 2017, from

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